| aa-AMP | aminoacyl-adenylate |
| aaRS | aminoacyl-tRNA synthetase |
| aa-tRNA | aminoacyl-tRNA |
| aaS3DA | aminoacyl sulfamoyl 3-deazaadenosine |
| aaSA | aminoacyl-sulfamoyl adenosine |
| aaSoA | 5′-(N-aminoacyl)-sulfonamido-5′-deoxyadenosine |
| aaSoHA | N-L-aminoacyl-C-5′-adenosyl-methansulfonamide |
| AdT | amidotransferase |
| AlaRS | alanyl-tRNA synthetase |
| AMP | adenosine monophosphate |
| AMPPNP | adenylyl-imidodiphosphate |
| AMR | antimicrobial resistance |
| AP | auxiliary pocket |
| ArgRS | arginyl-tRNA synthetase |
| AsnRS | asparaginyl-tRNA synthetase |
| AspRS | aspartyl-tRNA synthetase |
| ATP | adenosine triphosphate |
| CP1 | connective polypeptide 1 |
| CysRS | cysteinyl-RNA synthetase |
| DNA | Deoxyribonucleic acid |
| EC50 | half maximal effective concentration |
| EPRS | glutamyl prolyl-tRNA synthetase |
| ESBL | extended spectrum β-lactamase |
| FDA | Food and Drug Administration |
| GlnRS | glutaminyl-tRNA synthetase |
| GluRS | glutamyl-tRNA synthetase |
| GlyRS | glycyl-tRNA synthetase |
| GSA | glycyl-sulfamoyl adenosine |
| GSK | GlaxoSmithKline |
| HisRS | histidyl-tRNA synthetase |
| HTS | high-throughput screening |
| IC50 | half maximal inhibitory concentration |
| IleRS | isoleucyl-tRNA synthetase |
| ISA | isoleucyl-sulfamoyl adenosine |
| ITC | isothermal titration calorimetry |
| LeuRS | leucyl-tRNA synthetase |
| LSA | leucyl-sulfamoyl adenosine |
| LysRS | lysyl-tRNA synthetase |
| McC | microcin C |
| MDR | multidrug resistance |
| MetRS | methionyl-tRNA synthetase |
| MIC | minimum inhibitory concentration |
| MRSA | methicillin-resistant Staphylococcus aureus |
| Mtb | Mycobacterium tuberculosis |
| PDB | protein data bank |
| PheRS | phenylalanyl-tRNA synthetase |
| PPi | pyrophosphate |
| ProRS | prolyl-tRNA synthetase |
| PylRS | pyrrolysyl-tRNA synthetase |
| RF | Rossmann fold |
| RNA | ribonucleic acid |
| SAR | Structure-activity relationship |
| SBDD | structure-based drug design |
| SepRS | phosphoseryl-tRNA synthetase |
| SerRS | seryl-tRNA synthetase |
| SSA | seryl-sulfamoyl adenosine |
| ThrRS | threonyl-tRNA synthetase |
| Tm | melting temperature |
| tRNA | transfer RNA |
| TrpRS | tryptophanyl-tRNA synthetase |
| TSA | threonyl-sulfamoyl adenosine |
| TyrRS | tyrosyl-tRNA synthetase |
| ValRS | valyl-tRNA synthetase |
| WHO | World Health Organization |