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. 2021 Feb 10;22(4):1756. doi: 10.3390/ijms22041756

Figure 3.

Figure 3

Concomitant Bmpr2 mutation does not alter the pulmonary hypertension (PH) phenotype in Tnfaip3DNGR1-KO mice. (a) Right ventricular systolic pressure (RVSP), determined by right heart catheterization and hypertrophy of RV measured by Fulton index (right ventricle/ left ventricle + septum) of the indicated mouse groups; (b) quantification of lung CD103+CD11c+ cDC1 frequencies and CD86 expression (MFI = median fluorescence intensity) by flow cytometry; (c–f) quantification of CD64+GR1- monocyte/macrophage population (c), CD3+ T cells (d), memory CD44+CD62L- CD8+ T cells (e) or CD19+ B cells (f) determined by flow cytometry in the lungs of the indicated mouse groups. Results are presented as mean + standard deviation of 10–31 mice (a) or 4–12 mice (b–e) per group. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.