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. 2021 Feb 10;13(4):720. doi: 10.3390/cancers13040720

Table 2.

Differential metabolites (GC vs. non-GC) for gastric cancer.

Metabolite [47]
(Meta-Analysis n = 9)
Metabolite [10] Metabolite [2] Metabolite [48]
(Xiu)
Glycine ↑ Glycine ↓
Tyrosine Tyrosine ↓ Tyrosine ↓
Phenylalanine Phenylalanine ↓
Alanine Alanine ↓ Alanine ↑ Alanine ↓
Threonine Threonine Threonine ↓
Isoleucine Isoleucine ↓
Histidine Histidine ↓ Histidine ↓ Histidine ↓
Taurine Taurine
Arginine Arginine ↓ Arginine ↑
Leucine Leucine ↓
Methionine Methionine Methionine ↓
Valine Valine ↑
Serine ↑ Serine ↑
Tryptophan Tryptophan ↓ Tryptophan ↓ Tryptophan ↓
Fumarate
Cystine ↓
Asparagine Asparagine ↑ Asparagine ↑ Asparagine ↓
Lysine Lysine Lysine ↑ Lysine ↓
Propanoic acid
Pyruvic acid
Glutamate ↓
Glutamine Glutamine ↓ Glutamine ↓
Citrulline Citrulline Citrulline ↓
Spermidine Spermidine ↑
3-Hydroxypropionic acid
Metabolite [47] Metabolite [10] Metabolite [2] Metabolite [48]
(Xiu)
Anthranilic acid
Ornithine Ornithine ↑ Ornithine ↑
Sarcosine Sarcosine
Creatinine
2-Hydroxybutyrate
3-Hydroxyisobutyric acid
Erythro-isoleucine ↑
Symmetric dimethylarginine ↑
hydroxytetradecadienylcarnitine↑
Methionine sulfoxide ↑
Tetradecanoylcarnitine
Hexadecadienylcarnitine ↑
Octadecanoylcarnitine ↓
Xanthurenic acid Xanthurenic acid
Phenylacetylglutamine ↑
Octadecenoylcarnitine
N-formylkynurenine
Uric acid
d-Glucose
Melatonin
Serotonin
2-aminobenzoic acid
l-Kynurenine
Kynurenic acid
Tryptamine
3-Indoleactamide
(Indol-3-yl)acetamide
Indolacetic acid
6-Hydroxymelatonin
5-Methoxytryptamine
Indolelactic acid
Tryptophanol
Propionic acid
Quinolinic acid
Niacinamide
Homocysteine ↓

The arrows indicate reported increasing or decreasing trends relative to non-GC controls.