Table 3.

The metabolite profile of GC across Correa’s cascade [10].

NAG/GC Ratio	CAG/GC Ratio	PLGC/GC Ratio
Alanine 1.32 ↑	Alanine 1.36 ↑	Alanine 1.39 ↑
Asparagine 1.12 ↑	Asparagine 1.08 ↑	Asparagine 1.10 ↑
Histidine 1.22 ↑ *	Histidine 1.18 ↑ *	Histidine 1.14 ↑ *
Erythro-isoleucine 1.03 ↑	Erythro-isoleucine 0.96 ↓	Erythro-isoleucine 0.96↓
Ornithine 0.91↓	Ornithine 0.82 ↓	Ornithine 0.64↓
Symmetric dimethylarginine 0.79 ↓	Symmetric dimethylarginine 0.84 ↓	Symmetric dimethylarginine 0.70↓ *
Hydroxytetradecadienylcarnitine 0.87 ↓	Hydroxyteradecadienylcarnitine 0.82↓ *	Hydrocytetradecadienylcarnitine 0.85↓ *
Methionine sulfoxide 0.93 ↓	Methionine sulfoxide 0.83↓ *	Methionine sulfoxide 0.81 ↓ *
Sarcosine
Spermidine 0.92 ↓	Spermidine 0.88 ↓	Spermidine 0.94 ↓
Tetradecanoylcarnitine
Hexadecanoylcarnitine 0.88 ↓	Hexadecanoylcarnitine 0.85 ↓	Hexadecanoylcarnitine 0.88 ↓
Octadecanoylcarnitine 1.33 ↑	Octadecanoylcarnitine 1.50 ↑ *	Octadecanoylcarnitine 1.50 ↑ *
Xanthurenic acid
Phenylacetylglutamine 0.33 ↓ *	Phenylacetylglutamine 0.45 ↓*	Phenylacetylglutamine 0.45↓*
Tryptophan 1.63 ↑ *	Tryptophan 1.36 ↑ *	Tryptophan 1.31 ↑ *
	Lysine
	Methionine
	Threonine
	N-acetylornithine
	Hydroxyhexadecanoylcarnitine
	Octadecenoylcarnitine
	N-formylkynurenine
		Taurine

* Indicates statistical significance (p < 0.05). The arrows indicate the trend relative to GC.