Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 10;22(4):1767. doi: 10.3390/ijms22041767

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Sites of interaction between fetal-derived trophoblast and maternal immune cells in the pregnant woman. Trophoblast-derived material, entire cells and the multinucleated syncytiotrophoblast layer encounter maternal immune cells at no less than eight main sites. These can be divided into those that interact with systemic maternal immune cells in peripheral blood and peripheral tissues and those that encounter the specialized immune cell populations in the maternal decidua. EVT: extravillous trophoblast; evTB: endovascular trophoblast cells; iEVT: interstitial EVT; IVS: intervillous space; LN: lymph node; LV: lymphatic vessel; MD: maternal decidua; MM: maternal myometrium; MPV: maternal peripheral vessel; MSA: maternal spiral artery: pSTB: primitive syncytiotrophoblast, schCTBs: smooth chorionic cytotrophoblast cells; vSTB: villous syncytiotrophoblast.