Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Superimposition of all published FFAR1 crystallographic structures. The partial allosteric agonists TAK-875 and MK-8666 share the same binding site, denoted here as site A. Full allosteric agonists (AP8 and compound 1) are found in the second allosteric site, denoted here as site B. The respective PDB IDs are: 4PHU, 5TZY, 5TZR, and 5KW2. This figure was prepared using The PyMOL Molecular Graphics System, Version 2.0 Schrödinger, LLC (New York, NY, USA).
