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. 2020 Dec 24;180(1):1–16. doi: 10.1093/toxsci/kfaa181

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© The Author(s) 2020. Published by Oxford University Press on behalf of the Society of Toxicology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Principal component analysis of sRNA-seq normalized microRNA counts in nephron segments isolated by laser capture microdissection (LCM) in Sprague Dawley rats. A, Principal component 1 (PC1; x-axis) and PC2 (y-axis) view. B, PC3 (z-axis) view. First 3 PCs shown, representing 73% of the total variance. Each data point represents different sequencing lanes. Shapes designate individual rat samples. Colors represent different nephron regions (see key). Colored shaded regions represent groupings of each nephron segment sampled via LCM.