Table 4.
Summary of the Outcomes of Interest of the Included Studies with a Comparison of TBP vs. Non-TBP.
| Study | Biopsies | Melanoma Cases | Benign-to-Malignant Ratio | Mean/Median Breslow Index | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Numbers | Due to TBP | Due to Change of Existing /Tracked Lesion | Due to Newly Emerged Lesion | Number | Due to TBP | Due to Change of Existing /Tracked Lesion | Due to Newly Emerged Lesion | |||
| Retrospective Studies | ||||||||||
| Rademaker 2010 | n.r. | n.r. | n.r. | n.r. | n.r. | n.r. | n.r. | n.r. | n.r. | Breslow index with TBP (vs. register data): <0.75 mm: 69% (vs. 52%) 0.76–1.49: 21% (vs. 22%) 1.5-3.0: 8% (vs. 15%) >3.0 mm: 2% (vs. 11%) First visit average 0.87 mm (range 0.3–3.35) Follow-up average 0.67 (range 0.22–1.60 mm |
| Risser 2007 | Mean: 0.81 TBSE: 0.82 (51 in 29 patients) TBP: 0.8 (53 in 28 patients) |
n.r. | n.r. | n.r. | TBSE: 3 in 19 patients TBP: 0 in 16 patients |
n.r. | n.r. | n.r. | n.r. | Absolute: 0.3, 0.44 and 1.1 mm |
| Strunck 2020 | n.r. | n.r. | n.r. | n.r. | 121 (in situ 51, invasive 70) | 54 changing; 11 new | 65 | 12 | Median depth - 0.33 mm in follow-up group (range 0.11–1.5) - 0.83 mm in control group without follow-up (range 0.11–3.3) Median depth, if TBP was used: - 0.31 mm (range 0.11–1.5) Median depth without use of TBP: - 0.48 mm (0.10–3.3) |
|
| Truong 2016 | Pre-TBP 3489 biopsies in 589 patients (mean 5.92) Post-TBP 921 biopsies in 589 patients (mean 1.56) |
n.r. | n.r. | n.r. | Pre-TBP: 278 biopsies with 32 melanomas (in situ 14; invasive 18) Post-TBP: 1419 biopsies with 93 melanomas (in situ 46; invasive 47) |
n.r. | n.r. | n.r. | Pre-TBP 7.7 Post-TBP 14.3 |
Range: - Pre-TBP: 0.2–3.0 mm - Post-TBP: 0.11–2.1 mm |
Abbreviation: n.r. = not reported, TBP = total body photography, TBSE = total body skin examination.