Figure 1.

(A) Non-metric multi-dimensional scaling (NMDS) for the concentration of immune factors in maternal plasma (MP, n = 26) and umbilical cord plasma (UCP, n = 23). Categorical variable (type of sample) is represented by color (red for MP and blue for UCP). (B) Continuous variables are represented by vectors. Samples were clustered by type of plasma and the analysis of similarities (ANOSIM) test was used to determine if the immune composition was different in the different clusters, p = 0.0001. GM-CSF, Granulocyte Macrophage Colony-Stimulating Factor; IFN, Interferon; IL, Interleukin; TNF, tumor necrosis factor. IgG1, IgG2, and IgG3 (Igs associated with Th1 response); IgG4 (Ig associated with Th2 response) [30,31].