Table 2.
Cytokines | MP, n = 26 | UCP, n = 23 | ||||
---|---|---|---|---|---|---|
pg/mL | %det | IQR | pg/mL | %det | IQR | |
GM-CSF | 1.83 ± 0.98 | 15.38 (4/26) | 0.00–0.00 | 0.00 ± 0.00 | 0.00 (0/23) * | 0.00–0.00 |
IFN-γ | 20.17 ± 4.36 | 96.15 (25/26) | 7.02–26.43 | 1.80 ± 0.67 * | 39.13 (9/23) * | 0.00–2.12 |
IL-1β | 0.08 ± 0.08 | 3.85 (1/26) | 0.00–0.00 | 1.43 ± 0.56 * | 56.52 (13/23) * | 0.00–2.10 |
IL-2 | 1.62 ± 0.60 | 26.92 (7/26) | 0.00–4.51 | 9.27 ± 2.66 * | 52.17 (12/23) | 0.00–18.14 |
IL-4 | 17.58 ± 9.84 | 23.08 (6/26) | 0.00–6.50 | 0.53 ± 0.37 | 8.70 (2/23) | 0.00–0.00 |
IL-5 | 0.67 ± 0.36 | 42.31 (11/26) | 0.00–0.10 | 6.24 ± 3.30 | 56.52 (13/23) | 0.00–9.09 |
IL-6 | 10.57 ± 3.57 | 46.15 (12/26) | 0.00–12.42 | 13.72 ± 7.05 | 17.39 (4/23) * | 0.00–0.00 |
IL-9 | 5.60 ± 2.29 | 42.31 (11/26) | 0.00–9.46 | 0.95 ± 0.72 * | 17.39 (4/23) * | 0.00–0.00 |
IL-10 | 0.07 ± 0.07 | 7.69 (2/26) | 0.00–0.00 | 0.06 ± 0.04 | 13.04 (3/23) | 0.00–0.00 |
IL-12 | 0.31 ± 0.10 | 65.38 (17/26) | 0.00–0.44 | 0.15 ± 0.03 | 82.61 (19/23) | 0.05–0.24 |
IL-13 | 3.34 ± 1.09 | 38.46 (10/26) | 0.00–5.10 | 0.15 ± 0.15 * | 4.35 (1/23) * | 0.00–0.00 |
IL-17 | 3.46 ± 2.24 | 15.38 (4/26) | 0.00–0.00 | 4.88 ± 1.84 | 30.43 (7/23) | 0.00–12.16 |
IL-18 | 39.95 ± 5.81 | 100.00 (26/26) | 24.89–44.14 | 12.64 ± 2.40 * | 95.65 (22/23) | 4.53–16.96 |
IL-21 | 5.57 ± 1.71 | 50.00 (13/26) | 0.00–10.25 | 0.58 ± 0.39 * | 13.04 (3/23) * | 0.00–0.00 |
IL-22 | 2.86 ± 1.15 | 23.08 (6/26) | 0.00–1.75 | 0.00 ± 0.00 * | 0.00 (0/23) * | 0.00–0.00 |
IL-23 | 32.14 ± 7.87 | 80.77 (21/26) | 0.54–62.86 | 5.78 ± 4.17 * | 17.39 (4/23) * | 0.00–0.00 |
IL-27 | 25.59 ± 12.76 | 26.92 (7/26) | 0.00–13.36 | 0.81 ± 0.62 | 8.70 (2/23) | 0.00–0.00 |
TNF-α | 0.03 ± 0.02 | 11.54 (3/26) | 0.00–0.00 | 1.16 ± 0.65 * | 52.17 (12/23) * | 0.00–0.99 |
Data shown are expressed as mean ± S.E.M., detectability frequencies (%det), and interquartile ranges (IQRs). Mann–Whitney U test was used to determine significant differences between plasma samples. X2 test compared detectability. * p < 0.05. MP, maternal plasma; UCP, umbilical cord plasma; GM-CSF, Granulocyte Macrophage Colony-Stimulating Factor; IFN, Interferon; IL, Interleukin; TNF, tumor necrosis factor.