Table 3.
Concentrations and relative frequencies of immunoglobulins in maternal and umbilical cord plasma.
| Immunoglobulins | MP, n = 27 | UCP, n = 23 | |||
|---|---|---|---|---|---|
| mg/L | % | mg/L | % | ||
| Total | 11,261.98 ± 992.16 | - | 7524.38 ± 607.52 * | - | |
| IgM | 3151.52 ± 438.11 | 27.02 ± 1.92 | 671.94 ± 54.04 * | 9.66 ± 0.79 * | |
| IgG | 7703.94 ± 722.07 | 69.08 ± 1.97 | 6829.39 ± 595.40 | 90.02 ± 0.90 * | |
| IgG1 | 5911.40 ± 709.55 | 73.94 ± 1.71 | 5452.28 ± 532.65 | 78.63 ± 1.35 * | |
| IgG2 | 778.52 ± 60.11 | 11.36 ± 0.99 | 541.50 ± 70.35 * | 8.18 ± 0.70 * | |
| IgG3 | 892.46 ± 70.90 | 12.90 ± 1.17 | 737.07 ± 53.50 | 11.68 ± 0.87 | |
| IgG4 | 121.56 ± 12.55 | 1.79 ± 0.20 | 98.54 ± 14.42 | 1.51 ± 0.17 | |
| Th1 | 7582.38 ± 721.55 | 98.21 ± 0.20 | 6730.84 ± 589.38 | 98.49 ± 0.17 | |
| Th2 | 121.56 ± 12.55 | 1.79 ± 0.20 | 98.54 ± 14.42 | 1.51 ± 0.17 | |
| Th1/Th2 | 77.31 ± 10.24 | -- | 82.68 ± 7.98 | -- | |
| IgA | 405.77 ± 28.07 | 3.89 ± 0.22 | 22.68 ± 9.00 * | 0.32 ± 0.14 * | |
| IgE | 0.75 ± 0.06 | 0.0074 ± 0.0006 | 0.37 ± 0.03 * | 0.0051 ± 0.0003 * | |
Data shown are expressed as mean ± S.E.M. and relative frequencies (%). Mann–Whitney U test was used to determine significant differences between plasma samples. * p < 0.05. MP, maternal plasma; UCP, umbilical cord plasma. IgG1, IgG2, and IgG3 (Igs associated with Th1 response); IgG4 (Ig associated with Th2 response) [30,31].