Table 5.
Immunoglobulin composition of umbilical cord plasma from each maternal enterotype.
| Immunoglobulins | Enterotype I, n = 11 | Enterotype II, n = 11 | |||
|---|---|---|---|---|---|
| pg/mL | % | pg/mL | % | ||
| Total | 7591.44 ± 1011.25 | - | 7746.90 ± 759.91 | - | |
| IgM | 762.62 ± 99.96 | 11.14 ± 1.48 | 601.00 ± 41.08 | 8.10 ± 0.48 * | |
| IgG | 6786.45 ± 1007.05 | 88.23 ± 1.69 | 7140.09 ± 726.53 | 91.85 ± 0.47 * | |
| IgG1 | 5386.84 ± 920.83 | 77.52 ± 2.41 | 5722.82 ± 634.95 | 79.41 ± 1.51 | |
| IgG2 | 572.12 ± 123.57 | 8.94 ± 1.28 | 529.48 ± 83.70 | 7.38 ± 0.71 | |
| IgG3 | 715.23 ± 73.33 | 11.74 ± 1.32 | 799.95 ± 74.10 | 12.01 ± 1.26 | |
| IgG4 | 112.25 ± 24.92 | 1.80 ± 0.32 | 87.85 ± 17.17 | 1.20 ± 0.14 | |
| Th1 | 6674.20 ± 999.90 | 98.20 ± 0.32 | 7052.24 ± 714.40 | 98.80 ± 0.14 | |
| Th2 | 112.25 ± 24.92 | 1.80 ± 0.32 | 87.85 ± 17.17 | 1.20 ± 0.14 | |
| Th1/Th2 | 73.19 ± 11.83 | - | 94.37 ± 11.17 | - | |
| IgA | 41.98 ± 16.97 | 0.62 ± 0.26 | 5.44 ± 3.65 * | 0.05 ± 0.03 * | |
| IgE | 0.38 ± 0.05 | 0.0054 ± 0.0005 | 0.36 ± 0.04 | 0.0048 ± 0.0003 | |
Immunoglobulin composition in each enterotype is expressed as mean ± S.E.M. and relative frequencies (%). Mann–Whitney U tests were used to determine significant differences between groups of maternal enterotypes. * p < 0.05. IgG1, IgG2, and IgG3 (Igs associated with Th1 response); IgG4 (Igs associated with Th2 response) [30,31].