Table 2.
Disease | Associated Gut Microbiota | Additional Remarks | Reference |
---|---|---|---|
1. Acne vulgaris | Decrease in Firmicutes and increase in Bacteroides. | Distinct gut microbiome composition and decreased diversity. | [106] |
2. Atopic Dermatitis | Higher levels of Faecalibacterium prausnitzii, Clostridium, and Escherichia (in infants). Lower levels of Akkermansia, Bacteroidetes, and Bifidobacterium. | Probiotics consumption can prevent AD *. | [107,108,109,110,111,112,113,114] |
3. Psoriasis | Changes in -diversity. Gut microbiome changes in reaction to biologicals. | Increased risk of intestinal immune disorders. Diet and gut microbiome can have an impact on inflammation. | [115,116,117,118,119,120] |
4. Hidradenitis suppurativa | Unknown | Increased risk in developing CD * and UC *. | [121,122] |
5. Rosacea | Can be associated with SIBO *. Acidaminococcus and Megasphaera increase and Peptococcaceae and Methanobrevibacter decrease. | Can be associated with H. pylori infection. | [123,124,125] |
6. Dandruff and Seborrheic dermatitis | Unclear | Probiotic consumption can alleviate moderate to severe dandruff | [126] |
7. Alopecia areata | No major differences | FMT * in 2 patients showed restoration of hair growth | [127,128] |
8. Skin cancer | Not reported | Other cancers are associated with microbial dysbiosis | [129,130,131] |
9. Wound healing | Not reported | Not reported |
* Abbreviations: atopic dermatitis (AD), Crohn’s disease (CD), fecal microbiota transplant (FMT), hidradenitis suppurativa (HS), small intestinal bacterial overgrowth (SIBO), and ulcerative colitis (UC).