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. 2021 Feb 11;9(2):353. doi: 10.3390/microorganisms9020353

Table 2.

Gut microbiota associated with nine common skin disorders.

Disease Associated Gut Microbiota Additional Remarks Reference
1. Acne vulgaris Decrease in Firmicutes and increase in Bacteroides. Distinct gut microbiome composition and decreased diversity. [106]
2. Atopic Dermatitis Higher levels of Faecalibacterium prausnitzii, Clostridium, and Escherichia (in infants). Lower levels of Akkermansia, Bacteroidetes, and Bifidobacterium. Probiotics consumption can prevent AD *. [107,108,109,110,111,112,113,114]
3. Psoriasis Changes in β-diversity. Gut microbiome changes in reaction to biologicals. Increased risk of intestinal immune disorders. Diet and gut microbiome can have an impact on inflammation. [115,116,117,118,119,120]
4. Hidradenitis suppurativa Unknown Increased risk in developing CD * and UC *. [121,122]
5. Rosacea Can be associated with SIBO *. Acidaminococcus and Megasphaera increase and Peptococcaceae and Methanobrevibacter decrease. Can be associated with H. pylori infection. [123,124,125]
6. Dandruff and Seborrheic dermatitis Unclear Probiotic consumption can alleviate moderate to severe dandruff [126]
7. Alopecia areata No major differences FMT * in 2 patients showed restoration of hair growth [127,128]
8. Skin cancer Not reported Other cancers are associated with microbial dysbiosis [129,130,131]
9. Wound healing Not reported Not reported

* Abbreviations: atopic dermatitis (AD), Crohn’s disease (CD), fecal microbiota transplant (FMT), hidradenitis suppurativa (HS), small intestinal bacterial overgrowth (SIBO), and ulcerative colitis (UC).