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. 2021 Feb 11;10(4):698. doi: 10.3390/jcm10040698

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Summary of immunohistochemical findings. Only cases where information was available of individual markers are included. Estrogen receptor (ER) and progesterone receptor (PR) are nearly always negative, with PR as a more reliable negative marker. Mesonephric-like adenocarcinomas (MLAs) are characterized by staining with GATA binding protein 3 (GATA3) and/or thyroid transcription factor 1 (TTF1) with sometimes a reversed staining pattern. CD10 was predominantly positive in the tested cases but mostly focal. Calretinin is more often negative. All cases showed Paired box protein-8 (PAX8) positivity and p53 wild type expression. (*) = negative for TP53 mutation.