Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The quality assessment is based on a checklist adapted from the Cochrane Handbook for Systematic Reviews of Interventions. The pre-clinical (indicated by blue bar) and clinical studies (indicated by red bar) have been classified in high, medium, and low risk of bias.
