Table 1.

Major public databases relevant to epigenetic drug discovery

Database	Last update	Number of targets	Number of compounds	URLa	Refs
Human epigenetic enzyme and modulator database (HEMD)	2012	269	4377	http://mdl.shsmu.edu.cn/HEMD/	[22]
EpiDBase	2015	Not available	5784	www.epidbase.org/	[23]
EpiFactors	2015	815	–	http://epifactors.autosome.ru	[24]
Database of Epigenetic Modifiers (dbEM)	2016	167	–	http://crdd.osdd.net/raghava/dbem	[25]
Epigenomics chemical database	2018	54	7820	www.difacquim.com/d-databases/	[18]

^aLast accessed: 25 August 2020.