Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 15;12:630427. doi: 10.3389/fimmu.2021.630427

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Rico de Souza, Traboulsi, Wang, Fritz, Eidelman and Baglole.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

DRE-independent regulation of neutrophilic cytokines and adhesion molecule expression. B6.D2N-Ahr^d/J, Ahr^dbd/b6 and Ahr^dbd/dbd mice were exposed to CS for 3 days and cytokine mRNA assessed in whole lung homogenates. ICAM-1 levels were also evaluated by western blot. (A) Neutrophil cytokines—there was little difference in the induction of Cxcl1, Cxcl2, Tnf-α, il6, or cxcl5 between the three groups of mice (ns = not significant). Results are shown as means ± SEM (n = 4–5 mice per group). (B) ICAM-1 Western blot—Pulmonary ICAM-1 levels were consistent between the B6.D2N-Ahr^d/J, Ahr^dbd/b6, and Ahr^dbd/dbd mice. There was little perceptible difference between the three groups in response to CS. (C) ICAM-1 Densitometry—There was no significant change in ICAM-1 protein expression after acute CS exposure. Results are shown as means ± SEM (n = 4–5 female mice per group).