Table 3:
Studies clinical outcomes. eFTR: Endoscopic full-thickness resection, N/A: Not Applicable.
| Study | Procedure Time (Minutes) | Complete Resection (R0) Rate | Technical Success Rate | eFTR Resection Rate | Mean Diameter of Resected Specimen (mm) | Complications | Surgery secondary to complication | Technical failure | OTSC Fate | Hospital Stay (Days) | Follow up | Recurrence |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aepli P et al., 201718 | 63 (mean) | 29/33 (87.9%) | 29/33 (87.9%) | 25/31 (80.6%) | 27.0 | Minor bleeding (2), Major bleeding (1), Perforation (1) | N/A | Not reachable lesions (1), Snare malfunction (3) | Not reported | 3.1 (mean) | Based on histologic type of the resected tissue | Not reported |
| Andrisani et al.,20186 | 45 (mean) | 99/110 (90%) | 103/114 (90.3%) | 100/110 (90.9%) | 20.0 | Traumatic wall injury (4), Stenosis after the deployment of the clip (1), Appendicitis (1), Perforation (1), Postpolypectomy syndrome (1), Tenesmus and perineal pain (2), Major bleeding (1) | 2 | Snare malfunction (12), Not reachable lesions (4) | Spontaneously fallen off (100), In place (10), Removed Endoscopically (2) | 91/110 (82.7%) stayed one day, 19/110 (17.3%) as outpatient | 3 months in all pts | Residual/recurrent disease in only 7 pts on 3-month follow-up |
| Schmidt et al., 20185 | 50 (median) | 139/181 (76.8%) | 162/181 (89.5%) | 162/181 (89.5%) | Not reported | Minor bleeding (4),Appendicitis (3), Postpolypectomy (3), Recurrent Abdominal pain (1), Perforation (6), Enterocolonic fistula (1) | 4 | Snare malfunction (13) | Spontaneously fallen off (106/154), In place (48), Enodscopically removed (10) | 4 (median) | 3 months 154/181 | 19/154 |
| Valli et al., 201819 | 60 (Median) | 46/58 (79.3%) | 58/60 (96.7%) | 51/58 (87.9%) | 24.0 | Minor bleeding (2), Appendicitis (1), Incomplete OTSC deployment (1). | N/A | Not reachable lesions (2), Snare malfunction (4) | Spont. Fallen off (26), In place (4), Removed endoscopically (3), unknown (24) | Not reported | Mean 16 months | No recurrence reported. |
| Vitali et al., 201820 | 68 (mean) | 10/13 (76.9%) | 13/13 (100%) | Not reported | 17.0 | Postpolypectomy (2) | N/A | Snare malfunction (1) | N/A | 2.5 (mean) | 8.7±7.2 months | 3/11 |
| Van der Spek et al., 201817 | Not reported | 40/50 (80%) | 45/51 (88.2%) | 43/50 (86%) | 21.0 | Minor bleeding (4), Major bleeding (1), Perforation (1), Postprocedural cardiac event (1), urinary retention (1) | N/A | N/A | N/A | N/A | 42/48 130 days (+/−11 days) | 5/42 |
| Rahman et al., 201622 | 40 (Median) | 8/9 (88.9%) | 9/11 (81.8%) | 9/9 (100%) | 22.0 | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Ichkhanian et al., 201921 | 63 (mean) | 56/63 (88.9%) | 67/79 (84.8%) | N/A | N/A | Appendicitis (1), Perforation (1), Minor bleeding (3) | 2 | Snare malfunction (3), clip closure (1),, Not reachable lesion (1) | N/A | 0.4 | N/A | N/A |
| Velegraki el al., 201923 | 36.9 (mean) | 14/17 (82.3%) | 14/17 (82.3%) | N/A | N/A | Minor bleeding (1), Appendicitis (1), Recurrent abdominal pain of unknown cause (1) | 1 | Not reachable lesion (2), Macroscopically incomplete resection (1) | N/A | 1–3 days | 6/17 3-month follow up | No recurrence both macro and microscopically |