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. Author manuscript; available in PMC: 2021 Nov 15.
Published in final edited form as: Bioorg Med Chem. 2020 Sep 1;28(22):115734. doi: 10.1016/j.bmc.2020.115734

Figure 7.

Figure 7.

Levels of Aβ38, Aβ40, and Aβ42 in plasma and brain following daily oral administration of either vehicle or compound 64 to female 5–6 month-old Tg2576 mice (n = 12/dose) were measured following a 14-day treatment course. Percent reduction is indicated for the study. Aβ38, Aβ40, and Aβ42 peptide levels were determined using Meso Scale Sector 6000 Multiplex assays. Statistical analysis was performed using Graphpad Prism software and results are expressed as mean ± SEM, and ANOVA was used to detect a significant effect. *: p < 0.05. **: p < 0.005. ***: p < 0.0005.