Table 1.
Main features of the study population
| Overall (n = 312) | Discharged (n = 106) | Admitted. general ward (GW) (n = 168) | Admitted. intensive care unit (ICU) (n = 30) | Died in ER (n = 8) | P value (< 0.05) | |
|---|---|---|---|---|---|---|
| Age (years) | 64 (22–94) | 52.5 (22–88) | 71 (25–94) | 64 (38–75) | 83 (57–90) | *#§$ |
| Sex (male %) | 66.3 | 53.8 | 70.8 | 86 | 66.7 | *#§$ |
| BMI (kg/m2) | 26.2 (18.7–45.7) | 25 (18.7–45.7) | 26.5 (19–40.8) | 28 (20.8–39.2) | 30.6 (7.3–33.8) | |
| Arterial systolic pressure (mmHg) | 130 (80–190) | 130 (90–185) | 130 (89–190) | 135 (80–178) | 120 (85–160) | |
| Arterial diastolic pressure (mmHg) | 80 (50–120) | 80 (60–117) | 80 (50–120) | 80 (50–102) | 80 (55–110) | |
| Heart rate (bpm) | 89 (40–175) | 88 (40–130) | 89 (50–175) | 95 (55–120) | 85 (71–140) | |
| Respiratory rate (/min) | 20 (10–75) | 18 (10–44) | 20 (10–50) | 20 (10–37) | 29 (20–75) | |
| CRP (mg/dL) | 7.6 (0.01–43.9) | 2.2 (0.01–15.7) | 11.5 (0.04–44) | 17.9 (0.6–40.2) | 13.4 (2.6–35.7) | *#§$° |
| Hb (g/dL) | 13.9 (4.6–23.5) | 13.9 (10.1–17.1) | 13.7 (4.6–23.5) | 14.5 (10.5–16.6) | 13.5 (10.3–16.3) | |
| Lymphocytes (× 103/µl) | 0.9 (0.1–3.9) | 1.1 (0.4–2.9) | 0.8 (0.1–3.9) | 0.7 (0.2–1.4) | 0.8 (0.5–1.1) | #§ |
| LDH (mU/mL) | 329 (122–2578) | 241 (122–501) | 370 (183–2578) | 505 (215–1150) | 462 (210–783) | #§ |
| TnI (ng/mL) | 11 (2.5–44783) | 3 (2.5–125) | 15 (2.5–44783) | 14 (3–171) | 27.5 (18–183) | |
| CPK (mU/mL) | 130 (19–46737 | 93.5 (22–2130) | 136 (19–46737) | 256 (24–1041) | 121 (34–698) | |
| Creatinine (mg/dL) | 0.89 (0.37–17) | 0.77 (0.37–1.69) | 0.98 (0.44–4.3) | 0.99 (0.56–1.6) | 1.1 (0.7–17) | *$ˆ |
| PaO2/FiO2 | 306.7 (37.4–704.7) | 380.5 (216.7–704.8) | 261 (37.4–528.5) | 201.9 (67.2–474.3) | 174 (44.4–414.3) | *#§$ |
| PaCO2 (mmHg) | 32.7 (16.9–52) | 34.7 (18.5–43) | 32 (16.9–54.4) | 32 (24–40) | 35.1 (27.1–52) | § |
| PaO2 (mmHg) | 71.3 (31–359) | 80 (52–359) | 66.3 (31–285) | 61 (31.5–112) | 67 (36.7–256) | # |
| LUS score | 11 (0–25) | 4 (0–20) | 13 (0–25) | 17 (8–24) | 19 (6–24) | *#§° |
General features of the study cohort of consecutive patients with laboratory-confirmed COVID-19. Data are shown as median value (range)
ANOVA (Shapiro–Wilk): * discharged vs dead; # discharged vs ICU; § discharged vs GW; $ dead vs IC; ° GW vs ICU; ˆ dead vs GW