Table 3.
Comparison of genotypes and alleles of GSK-3β rs6438552, rs334558, and rs2199503 gene polymorphisms between the depression and control groups.
| SNPs | Group | Genotype frequencies | p | Allele frequencies | p | |||
|---|---|---|---|---|---|---|---|---|
| rs6438552 | AA | AG | GG | A | G | |||
| MDD | 132 (24.0) | 316 (57.5) | 102 (18.5) | 0.00 | 580 (52.7) | 520 (47.3) | 0.00 | |
| Control | 98 (17.8) | 245 (44.3) | 209 (37.9) | 441 (39.9) | 663 (60.1) | |||
| rs334558 | AA | AG | GG | A | G | |||
| MDD | 109 (19.8) | 300 (54.6) | 141 (25.6) | 0.00 | 518 (47.1) | 582 ((52.9) | 0.00 | |
| Control | 81 (14.7) | 243 (44.0) | 228 (41.3) | 405 (36.7) | 699 (63.3) | |||
| rs2199503 | GG | AG | AA | G | A | |||
| MDD | 97 (17.6) | 293 (53.3) | 160 (29.1) | 0.00 | 487 (44.3) | 613 (55.7) | 0.00 | |
| Control | 68 (12.3) | 233 (42.2) | 251 (45.5) | 369 (33.4) | 735 (66.6) |