TABLE 1.
Mouse body and plasma parameters. Data present as Average ±SEM.a,b,c indicate a significant difference among different treatments (n = 20; p < 0.05).
| Control | Carotene 1 | Carotene 10 | Carotene 50 | |
|---|---|---|---|---|
| Body weight (g) | 32.44 ± 2.25 | 36.54 ± 1.00 | 36.37 ± 1.38 | 35.34 ± 0.82 |
| Testis index (% of body weight) | 0.84 ± 0.074 | 0.67 ± 0.029 | 0.73 ± 0.027 | 0.72 ± 0.023 |
| Kidney index (% of body weight) | 1.94 ± 0.167 | 1.71 ± 0.082 | 1.70 ± 0.034 | 1.70 ± 0.059 |
| Spleen index (% of body weight) | 0.42 ± 0.05 | 0.36 ± 0.02 | 0.31 ± 0.02 | 0.33 ± 0.02 |
| Liver index (% of body weight) | 6.33 ± 0.52a | 5.34 ± 0.22 bc | 5.50 ± 0.12 bc | 5.62 ± 0.22b |
| E2 (ng/L) | 251.84 ± 8.87 | 291.75 ± 29.99 | 291.75 ± 17.52 | 286.68 ± 13.52 |
| Testosterone (ng/L) | 47.64 ± 3.69 | 30.40 ± 5.42 | 33.20 ± 6.20 | 37.48 ± 9.58 |
| ALT | 35.77 ± 0.77 | 34.83 ± 1.60 | 35.46 ± 0.82 | 34.37 ± 0.71 |
| AST | 70.6 ± 3.7 | 55.1 ± 1.6 | 66.4 ± 2.94 | 65.7 ± 3.0 |
| Busulfan | B + carotene 1 | B + carotene 10 | B + carotene 50 | |
| Body weight (g) | 32.50 ± 0.55 | 32.86 ± 0.79 | 33.82 ± 0.56 | 35.73 ± 0.75 |
| Testis index (% of body weight) | 0.24 ± 0.009 | 0.21 ± 0.006 | 0.21 ± 0.012 | 0.19 ± 0.011 |
| Kidney index (% of body weight) | 1.72 ± 0.029 | 1.75 ± 0.063 | 1.65 ± 0.067 | 1.62 ± 0.048 |
| Spleen index (% of body weight) | 0.39 ± 0.016 | 0.38 ± 0.014 | 0.39 ± 0.019 | 0.31 ± 0.011 |
| Liver index (% of body weight) | 5.00 ± 0.098 | 4.80 ± 0.085 | 4.85 ± 0.105 | 5.62 ± 0.122 |
| E2 (ng/L) | 329.13 ± 29.15 | 273.31 ± 29.99 | 378.34 ± 21.88 | 422.15 ± 21.19 |
| Testosterone (ng/L) | 43.92.±7.29 | 33.92 ± 9.78 | 39.84 ± 6.12 | 40.40 ± 8.66 |
| ALT | 37.38 ± 1.13 | 38.71 ± 0.50 | 35.45 ± 1.08 | 38.80 ± 1.53 |
| AST | 78.6 ± 3.72 | 84.36 ± 7.91 | 75.56 ± 4.98 | 80.53 ± 8.87 |