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Env-specific and Gag-specific CD4 TFH responses. Two weeks after the second and third immunizations, frequency of CD4 TFH in inguinal lymph nodes was assessed after stimulation with CAP257 54wpi_D Env trimeric glycoprotein or a pool of 125 SIVmac239 Gag open reading frame (ORF) 15-mer overlapping peptides. Data are expressed as percentage of functional CD4 TFH cells stimulated by vaccine immunogens. Tabulated data show mean +/- SEM.
