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. 2021 Feb 15;11:626464. doi: 10.3389/fimmu.2020.626464

Table 1.

Vaccine components included in each strategy.

Strategy Immunization #1 Immunization #2 Immunization #3
DNAa/SAd7b Proteinc DNAa/SAd7b Proteinc DNAa/SAd7b Proteinc
DNA +
Protein
54wpi_D
SIV Gag
54wpi_D 54wpi_D
SIV Gag
54wpi_D 54wpi_D
54wpi_C
54wpi_G
54wpi_D
SAd7 +
Protein
54wpi_D
SIV Gag
54wpi_D
SIV Gag
54wpi_D 54wpi_D

aDNA plasmid expresses Env gp160 heterotrimer, where each protomer is 160 kDa with an intact cleavage site.

bSAd7 vector expresses Env gp160 heterotrimer, where each protomer is 160 kDa with an intact cleavage site.

cHIV Envelope purified glycoprotein is a trimer, where each protomer is 140 kDa, no cleavage site.