TABLE 2.
Biochemical and Complete Blood Count Parameters of Healthy Controls and Patients With Cirrhosis
| Healthy Controls | Patients With Cirrhosis | P Value | |||
|---|---|---|---|---|---|
| n | Mean ± SD, range | n | Mean ± SD, range | ||
| Biochemistry/liver injury | |||||
| Sodium (mmol/L) | 17 | 140.2 ± 2.01, 136‐143 | 21 | 136.43 ± 4.47, 125‐149 | 0.0002 |
| BUN (mg/dL) | 17 | 15.35 ± 4.26, 9‐26 | 21 | 32.76 ± 24.97, 7‐111 | 0.0006 |
| Creatinine (mg/dL) | 17 | 0.93 ± 0.2, 0.48‐1.30 | 21 | 1.65 ± 0.87, 0.58‐4.00 | 0.002 |
| ALT (U/L) | 10 | 22.60 ± 12.44, 12‐50 | 21 | 35.57 ± 27.49, 9‐111 | 0.2539 |
| AST (U/L) | 9 | 23.78 ± 4.41, 17‐31 | 21 | 74.33 ± 47.72, 24‐165 | <0.0001 |
| ALP (U/L) | 9 | 63.44 ± 33.17, 4‐101 | 21 | 150.3 ± 52.47, 83‐268 | <0.0001 |
| Total bilirubin (mg/dL) | 9 | 0.62 ± 0.34, 0.3‐1.3 | 21 | 11.80 ± 11.55, 0.5‐37.9 | <0.0001 |
| Albumin (g/dL) | 9 | 4.32 ± 0.38, 3.4‐4.7 | 21 | 3.11 ± 0.58, 1.8‐4.2 | <0.0001 |
| INR | 0 | — | 21 | 2.05 ± 0.72, 1.1‐4.2 | — |
| MELD | — | — | 21 | 27.86 ± 9.23, 13‐45 | — |
| Complete blood cell counts | |||||
| WBC count (103/μL) | 14 | 6.57 ± 1.73, 3.7‐10.04 | 21 | 8.32 ± 4.29, 2.84‐18.44 | NS |
| ANC (103/μL) | 7 | 3.43 ± 1.07, 2.19‐5.32 | 14 | 6.24 ± 3.46, 1.9‐14.59 | 0.0379 |
| Hb (g/dL) | 14 | 14.24 ± 1.28, 12.1‐17 | 21 | 8.58 ± 1.43, 7‐12.2 | <0.0001 |
| Platelets (103/μL) | 14 | 274.6 ± 68.06, 166‐390 | 21 | 85.52 ± 82.03, 15‐311 | <0.0001 |
Data are presented as mean ± SD as appropriate. P values represent Mann‐Whitney U test results.
Abbreviations: INR, international normalized ratio; NS, no significance.