TABLE 1.
Variable n (%) or Median (IQR) | ALD (42 Patients) | Others (40 Patients) | P Value* |
---|---|---|---|
Male sex | 27/42 (64%) | 14/40 (35%) | 0.01 |
Female sex | 15/42 (36%) | 26/40 (65%) | 0.01 |
Age (years) | 57.5 (51‐62) | 61 (56.75‐66.25) | 0.07 |
Hispanic ethnicity | 13/42 (31%) | 9/40 (22%) | 0.46 |
Non‐Hispanic ethnicity | 29/42 (69%) | 31/40 (77%) | 0.46 |
White race | 20/42 (48%) | 18/40 (45%) | 0.83 |
Asian race | 0/42 (0%) | 5/40 (12%) | 0.05 |
Hispanic race | 13/42 (31%) | 9/40 (22%) | 0.46 |
African American race | 2/42 (5%) | 3/40 (7%) | 0.67 |
Public insurance | 11/42 (26%) | 16/40 (40%) | 0.24 |
Medicare + commercial insurance | 31/42 (74%) | 24/40 (60%) | 0.24 |
Received LT | 15/42 (36%) | 6/40 (15%) | 0.04 |
Listed for LT | 16/42 (38%) | 11/40 (27%) | 0.35 |
Declined for LT | 19/42 (45%) | 16/40 (40%) | 0.66 |
ALP (U/L) | 136.5 (89.25‐193) | 145 (104.5‐203.25) | 0.41 |
Albumin (g/dL) | 2.65 (1.93‐3.6) | 2.7 (2.05‐3.1) | 0.65 |
ALT (U/L) | 34.5 (24.25‐54) | 52 (26.75‐168) | 0.02 |
AST (U/L) | 67.5 (45‐100.75) | 101.5 (49.5‐305) | 0.05 |
Creatinine (mg/dL) | 1.71 (0.84‐2.34) | 1.195 (0.75‐2.25) | 0.46 |
INR | 2.45 (1.8‐3.05) | 1.95 (1.675‐2.6) | 0.18 |
Sodium (mmol/L) | 132 (126‐134.75) | 135 (131.75‐140) | 0.005 |
Total bilirubin (mg/dL) | 9.85 (5.275‐15.775) | 7.15 (3.3‐18.95) | 0.51 |
MELD‐Na score | 33 (28.25‐36) | 28 (25.25‐33) | 0.06 |
CLIF‐C score | 55 (49‐60.75) | 54.5 (51‐58) | 0.74 |
SIPAT score | 34 (25‐44) | 23 (18‐30) | 0.0005 |
ACLF grade 3 | 11/42 (26%) | 7/40 (17%) | 0.43 |
Referred from floor | 39/42 (93%) | 35/40 (87%) | 0.48 |
Referred from ICU | 3/42 (7%) | 5/40 (13%) | 0.48 |
Vasopressor support | 2/42 (4.8%) | 4/40 (10%) | 0.42 |
Respiratory failure | 1/42 (2.4%) | 6/40 (15%) | 0.05 |
HRS | 12/42 (28.6%) | 3/40 (7.5%) | 0.02 |
HE | 16/42 (38%) | 14/40 (35%) | 0.82 |
P < 0.05 is considered significant.
Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HE, hepatic encephalopathy; INR, international normalized ratio.