FIG. 6.

Reversal of the FADS1‐KD effects with FF (A) or FGF21 (B) treatment. Control or FADS1‐KD HepG2 cells were treated with vehicle (NT), medium PA/OA, medium PA/OA + FF (50 nM), or medium PA/OA + FGF21 protein (10 nM and 30 nM) for 24 hours. *P < 0.05, **P < 0.01, or ***P < 0.001 as compared with the control shRNA cells; ^# P < 0.05, ^## P < 0.01, or ^### P < 0.001 as compared with the FADS1‐KD cells treated with PA/OA. Data of a representative experiment (in triplicates) of independent performances are shown.