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. 2021 Feb 24;16:1405–1422. doi: 10.2147/IJN.S291090

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© 2021 Gao et al.

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IG-loaded dual-functional NPs (DFNPs) attenuated the changes in body weight loss (A), macroscopic score (B), and DAI (C) during the experimental period. Rats were orally treated with IG-loaded different NPs at a dose of IG 30 mg/kg once for 14 days after administration of DSS.

Notes: Data are presented as the mean ± SD (n = 6 per group). ## p < 0:01 vs the normal control group; ** p < 0.01 vs the DSS-induced colitis group; §§ p < 0.01 vs IG-loaded time-dependent NPs (TNPs) group; ★★ p < 0.01 vs IG-loaded pH-sensitive NPs (PNPs) group.Notes: