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. 2021 Feb 18;16:1361–1376. doi: 10.2147/IJN.S291285

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© 2021 Chen et al.

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TGMF inhibits tumor cell viability and invasion. (A) XPNPEP2 expresses in SKOV-3, A375, HeLa, PC3 and A549 cell lines. (B) Elisa was used to detect the relative expression of MMP-2 in the culture medium of SKOV-3, A375, HeLa, PC3 and A549 cell lines. (C) Western blot was used to detect the expression of MUC1 in SKOV-3, A375, HeLa, PC3 and A549 cell lines. The effect of PBS (D) or TGF (E), TMF (F), TGM (G), GMF (H) and TGMF (I) on cell viability tested by CCK-8 assay. (J) The invasion ability of HeLa cells treated with PBS, TGM, TGF, TMF, GMF and TGMF was detected by transwell assay. (K) Compared to PBS, TGF, TMF, GMF and TGMF rather than TGM significantly restrained the migration of Hela cells and TGMF suppressed cell movement most significantly. Data were presented as the mean ± SD (n =3) and analyzed by two-sided Student’s t-test. * p <0.05, ** p <0.01 *** p <0.001.