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. 2021 Feb 22;14:479–493. doi: 10.2147/JIR.S292764

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© 2021 Meng et al.

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NMN regulated macrophage phagocytosis and polarization in the CEC/macrophage co-culture system. (A) The phagocytosis ability in macrophage cultured with control CEC, CEC in HS, NMN-treated CEC in HS and CEC in HS in combination of anti-IL-17a treatment. (B) The mRNA expression of M1 related genes in macrophage cultured with control CEC, CEC in HS, NMN-treated CEC in HS and CEC in HS in combination of anti-IL-17a treatment, n=4, data presented as mean ± SD. One-way ANOVA with SNK multiple comparisons test. *Comparing with the control group, P<0.05; ^#comparing with the HS group, P<0.05. (C) The mRNA expression of M2 related genes in macrophage cultured with control CEC, CEC in HS, NMN-treated CEC in HS and CEC in HS in combination of anti-IL-17a treatment, n=4, data presented as mean ± SD. One-way ANOVA with SNK multiple comparisons test. *Comparing with the control group, P<0.05; ^#comparing with the HS group, P<0.05.