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. 2021 Feb 7;64(4):1856–1872. doi: 10.1021/acs.jmedchem.0c01886

Figure 1.

Figure 1

Chemical structures of early stage sEHI. A commonly used four-letter abbreviation and a University of California (UC) number are provided. Our lead compound in this series was DCU. The presence of an adamantyl group made the sEHI more potent and easier to detect by LC-MS in blood. They also tended to mimic EpFA, which were the presumptive substrates.