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. 2021 Mar 1;2(3):100222. doi: 10.1016/j.xcrm.2021.100222

Table 3.

Symptom severity, healthcare use, and suspected causes of symptoms, stratified by COVID-19 suspicion in individuals positive and negative for SARS-CoV-2 antibodies

COVID-19 diagnosed or suspected COVID-19 not suspected p
Positive for SARS-CoV-2 antibodies n = 125 n = 114

 Symptom severity (%)

  Asymptomatic 4 (3.2) 22 (19.3) <0.001
  Only very mild symptoms 17 (13.6) 47 (41.2)
  Mild to severe symptoms 104 (83.2) 45 (39.5)

 Clinically suspected COVID-19 (%)a 119 (95.2) 55 (48.2) <0.001

 Contacted a physician (%) 15 (12.0) 15 (13.2) 0.947

 Admitted to hospital 0 (0.0) 1 (0.9) 0.477

 Likely cause of symptoms, if any (%)

  Temporary illness 106 (84.8) 23 (20.1) <0.001
  Chronic complaints 0 (0.0) 4 (3.5)
  Unrelated circumstancesb 5 (4.0) 44 (38.6)
  Unknown 10 (8.0) 20 (17.5)

Negative for SARS-CoV-2 antibodies n = 435 n = 2993

 Symptom severity (%)

  Asymptomatic 31 (7.1) 1017 (34.0) <0.001
  Only very mild symptoms 74 (17.0) 1172 (39.2)
  Mild to severe symptoms 330 (75.9) 804 (26.9)

 Clinically suspected COVID-19 (%)a 365 (83.9) 982 (32.8) <0.001

 Contacted a physician (%) 50 (11.5) 205 (6.8) 0.001

 Admitted to hospital (%) 1 (0.2) 13 (0.4) 1.000

Numbers (percentage within COVID-19 suspicion status) are shown; differences tested with χ2 test or Fisher’s exact test in the event of cells with expected counts <5.

a

According to clinical criteria of WHO COVID-19 Case Definition (see Method details).

b

Circumstances not related to COVID-19, such as allergies or trauma.