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. 2021 Feb 23;6(9):2905–2913. doi: 10.1016/j.bioactmat.2021.02.014

Fig. 1.

Fig. 1

Characterization of CXCR4+ exosomes. A) Schematic illustration of exosome-guided miRNA blocking. B) Schematic illustration of CXCR4+ exosomes construction. C) CXCR4 expression levels in NIH-3T3 cells (3T3) and CXCR4-expressing NIH-3T3 cells (3T3-R4) determined by RT-qPCR (p < 0.0001). D) Western blotting results of exosome markers (Tsg101, CD9, and CD63) and CXCR4 in 3T3-R4 exosomes. E) TEM results showing the classical bilayer structure (black arrow) of CXCR4+ exosomes (scale bar = 100 nm). F) NTA results demonstrating the size distribution of CXCR4+ exosomes.