Skip to main content
. 2021 Feb 9;11:587590. doi: 10.3389/fphar.2020.587590

FIGURE 3.

FIGURE 3

Chemical characterization and proposal for passive diffusion: (A) Electrostatic potential surfaces between metformin and aromatic amino acids considered: tyrosine, histidine, phenylalanine, and tryptophan; (B) Interaction sequence and translocation movement of metformin in the hOCT1 organic cation channel.