Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic overview of factors influencing plasma concentrations of endoxifen. Known factors are genetic influences (e.g., CYP2D6 polymorphisms but also non-CYP2D6 polymorphisms), drug–drug interactions (e.g., concomitant use of CYP2D6 inhibitors), other factors (e.g., food, lifestyle, gender, age), tamoxifen dose, treatment adherence, and additional unknown factors.
