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. 2021 Feb 12;22(4):1858. doi: 10.3390/ijms22041858

Figure 2.

Figure 2

Knock down of δ-ENaC in A549 cells attenuated the tumor necrosis factor (TNF)-induced activation of ENaC. (A) Left panel, representative traces of whole-cell (10 µM) amiloride-sensitive ENaC currents at 100 mV of indicated experimental settings are shown. Right panel, IV plots of whole-cell currents of indicated experimental settings are shown. (B) Mean values of whole-cell inward sodium currents at −100 mV of indicated experimental settings are shown. Significant differences are indicated, *** p < 0.001, unpaired Student’s t-test, n = 12–15.