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Overexpression of N-linked glycosylation sites mutated δ-ENaC (3NQ) restored the TNF mediated activation of ENaC in δ-ENaC KD A549 cells. (A) IV plots of whole-cell (10 µM) amiloride-sensitive ENaC currents of indicated experimental settings are shown. (B) Mean values of whole-cell inward sodium currents at −100 mV of indicated experimental settings are shown. Significant differences are indicated, *** p < 0.001, unpaired Student’s t-test, n = 12–15.
