Figure 5.

The effect of complexes 1, 2 and 3 on glutathione peroxidase (GPx) activity in culture of noncancerous cells CHO-K1 (A) and tumour HepG2 cells (B). The cells (2 × 10⁴/well) were exposed to 50 μM/L of each compound or comparator salt for 24 h. Note that complex 3 decreased GPx activity in cancer cells (B) and complexes 1 and 2 elevated the enzyme activity in noncancerous cells (A). The enzyme activity was determined spectrophotometrically. The bars represent arithmetic mean values and standard deviation (M; ±SD) (n = 3; * p < 0.05 vs. untreated control).