Table 1.

HMGA2 expression changes in different cancer types. Data compare cancer tissues to normal tissues. The cut-offs including p-value = 0.01, fold change = 1.5, and gene ranking = 10%.

Cancer	HMGA2 Status	Sample Size	Fold Change	p-Value	Reference
Bladder cancer	Down	60	−1.576	5.55 × 10−8	[37]
Brain and CNS cancer	Up	85	21.74	8.16 × 10−5	[38]
Breast cancer	Up	593	1.58	1.14 × 10−4	TCGA
	Up	66	1.57	0.003	[39]
	Down	59	−23.054	1.58 × 10−23	[40]
Colorectal cancer	Down	40	−2.51	1.15 × 10−6	[41]
Esophageal cancer	Up	34	5.093	5.32 × 10−6	[42]
	UP	106	1.785	1.06 × 10−10	[43]
Gastric cancer	Down	132	−1573	0.001	[44]
Head and neck cancer	UP	99	2.045	2.05 × 10−6	[45]
	UP	18	6.098	3.11 × 10−5	[46]
	UP	38	3.657	7.34 × 10−7	[47]
	UP	18	9.926	6.31 × 10−6	[48]
	UP	20	2.877	0.001	[49]
	UP	54	2.368	2.06 × 10−7	[50]
	UP	84	3.781	2.45 × 10−5	[51]
	UP	41	2.130	5.93 × 10−5	[52]
Leukemia	Down	293	−2.087	0.005	[53]
Lung cancer	Up	66	2.320	3.18 × 10−5	[54]
	Up	246	3.001	1.39 × 10−12	[55]
	Up	73	3.999	0.005	[56]
	Up	156	11.019	1.01 × 10−10	[57]
Lymphoma	Down	136	−1.798	1.14 × 10−11	[58]
Melanoma	Up	87	2.664	8.13 × 10−4	[59]
Ovarian cancer	Up	594	2.965	1.16 × 10−5	TCGA
Pancreatic cancer	Up	52	3.629	1.17 × 10−7	[60]
Prostate cancer	Up	15	126.524	1.15 × 10−7	[61]
	Down	35	−4.150	9.90 × 10−6	[62]
	Down	102	−1.681	0.007	[63]
Sarcoma	Up	158	2.565	3.55 × 10−6	[64]

TCGA: The Cancer Genome Atlas Program.