Figure 2.

(A) Scheme of PSi functionalization through thermal oxidation and silanization with APTES or APDMES. Reprinted with permission from Reference [60]. (B) (a) Scheme of oxidized porous silicon modified through a ring-opening click reaction; (b) structure of reagents used for the study—thia-silane (DMTSCP, 2,2-dimethoxy-1-thia-2-silacyclopentane), butyl-aza-silane (BADMSCP, N-n-butyl-aza-2,2-dimethoxy-silacyclopentane), diaza-silane (DMDASCP, 2,2-dimethoxy-1,6-diaza-2-silacyclooctane), and methyl-aza-silane (MATMSCP, N-methyl-aza-2,2,4-trimethyl-silacyclopentane). R₁ = OMe, Me. R₂ = H, Me. Reprinted with permission from Reference [65] https://pubs.acs.org/doi/10.1021/jacs.6b08614 (accessed on 16 December 2020). Copyright (2016) American Chemical Society. (C) (a) Cartoons of randomly immobilized antibodies via physical adsorption and (b) properly orientated on the PSi matrix by using an intermediate layer of Protein A. Reprinted with permission from Reference [67] https://creativecommons.org/licenses/by/4.0/ (accessed on 16 December 2020).