NDI	Natural compound–drug interaction
BBB	Blood–brain barrier
BCSFB	Blood–cerebrospinal fluid barrier
ADME	Absorption, distribution, metabolism, and excretion
ISF	Interstitial fluid
CSF	Cerebrospinal fluid
CP	Choroid plexus
TJ	Tight junction
AJ	Adherence junction
JAM	Junctional adhesion molecule
ZO	Zonula occluden
CYP	Cytochrome P450
SLC	Solute carrier
ATP	Adenosine triphosphate
OATP	Organic anion transporting polypeptide
OAT	Organic anion transporter
OCT	Organic cation transporter
LAT	l-amino acid transporter
PEPT	Peptide transporter
GLUT	Glucose transporter
OCTN	Novel organic cation transporter
ABC	ATP-binding cassette
P-gp	P-glycoprotein
MRP	Multidrug resistance-associated protein
BCRP	Breast cancer resistance protein
GI	Gastrointestinal
BSEP	Bile salt export pump
MATE	Multidrug and toxin extrusion transporter
AD	Alzheimer’s disease
CBZ	Carbamazepine
PNT	Phenytoin
SJW	St John’s wort
DCT	Docetaxel
GB	Ginkgo biloba
ChEI	Cholinesterase inhibitor
CL	Systemic clearance
F	Oral bioavailability
PPD	Protopanaxadiol
CNS	Central nervous system
PG	Panax ginseng
QUE	Quercetin
PXR	Pregnane-X-receptor
BMEC	Brain microvascular endothelial cell
Rho	Rhodamine
CL	Curcuma longa
BEC	Brain capillary endothelial cell
DOX	Doxorubicin