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Anti-inflammatory activity of the MeOH extract of C. sativa (Marrone di Roccadaspide) leaves, burs, and chestnuts by in vitro nuclear factor-kappa B (NF-κB) activation assay (A) and nitric oxide (NO) production assay (B). Results are expressed as mean ± SE for three independent experiments. Significant difference in comparison to vehicle only treated cells (p < 0.001). + control = cells + LPS; -control = only cells.
