Table 2.
Sensitivity, specificity, positive predictive value and negative predictive value of different risk stratifiers’ cut-off values with regard to identification of subjects with screen-detected AF, as confirmed by 12-lead ECG.
| Sensitivity | Specificity | PPV | NPV | |
|---|---|---|---|---|
| % | % | % | % | |
| Age ≥ 65 (1848 [65.7%]) | 96.4 | 24.2 | 2.9 | 99.8 |
| Age ≥ 75 (691 [24.6%]) | 50 | 76 | 4.1 | 98.7 |
| CHA2DS2VASc > 0 in males and >1 in females or CHA2DS2VA > 0 (2163 [76.9%]) |
98.2 | 23.6 | 2.5 | 99.8 |
| CHA2DS2VASc > 1 in males and >2 in females or CHA2DS2VA > 1 (1510 [53.7%]) | 92.9 | 47.1 | 3.4 | 99.7 |
| CHA2DS2VASc > 2 (1185 [42.1%]) | 80.4 | 58.7 | 3.8 | 99.3 |
| CHA2DS2VASc > 3 (530 [18.8%]) | 42.9 | 81.7 | 4.5 | 98.6 |
| CHA2DS2VA > 2 (781 [27.8%]) | 73.2 | 73.2 | 5.2 | 99.3 |
| CHADS2 > 0 (1708 [60.7%]) | 92.9 | 40 | 3 | 99.6 |
| CHADS2 > 1 (722 [25.7%]) | 69.6 | 75.2 | 5.4 | 99.2 |
| CHADS2 > 2 (196 [7%]) | 23.2 | 93.4 | 6.6 | 98.4 |
| CHADS265 > 0 (2150 [76.4%]) | 98.2 | 24 | 2.6 | 99.8 |
| CHADS265 > 1 (1255 [44.6%]) | 89.3 | 56.3 | 4 | 99.6 |
| CHADS265 > 2 (336 [11.9%]) | 37.5 | 88.6 | 6.3 | 98.6 |
Legend: PPV: Positive predictive value; NPV: Negative predictive value.