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. 2021 Feb 12;10(4):729. doi: 10.3390/jcm10040729

Table 3.

For subjects aged ≥ 65 (n = 1848) sensitivity, specificity, positive predictive value and negative predictive value of different cut-offs of risk stratifiers, and age ≥ 75, with regard to identification of subjects with screen-detected AF, as confirmed by 12-lead ECG.

Sensitivity Specificity PPV NPV
% % % %
Age ≥ 75 (691 [37.4%]) 51.9 63.1 4.1 97.8
CHA2DS2VASc > 1 in males and >2 in females or CHA2DS2VA > 1 (1432 [77.5%]) 94.4 23 3.6 99.3
CHA2DS2VASc > 2 (1141 [61.7%]) 81.5 38.9 3.9 98.6
CHA2DS2VASc > 3 (522 [28.2%]) 44.4 72.2 4.6 97.7
CHA2DS2VA > 2 (767 [41.5%]) 75.9 59.5 5.3 98.8
CHADS2 > 0 (1406 [76.1%]) 94.4 24.5 3.6 99.3
CHADS2 > 1 (678 [36.7%]) 70.4 64.3 5.6 98.6
CHADS2 > 2 (187 [10.1%]) 24.1 90.3 7 97.5
CHADS265 > 1 (1211 [65.5%]) 90.7 35.2 4 99.2
CHADS265 > 2 (327 [17.7%]) 38.9 82.9 6.4 97.8

Legend: PPV: Positive predictive value; NPV: Negative predictive value.