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. 2021 Feb 14;10(2):288. doi: 10.3390/antiox10020288

Figure 7.

Figure 7

Neonates born to dams with prolonged Se deficient exhibit decreased pulmonary, renal, and cardiac GPx activity. C57Bl/6 mice were placed on diets that differed only in Se content, either 0.4 ppm or <0.01 ppm of sodium selenite. Breeding was initiated after 2–4 weeks on diet and natural delivery was allowed. Hepatic, cardiac, renal, and pulmonary organ homogenate was evaluated on day of birth. Each data point represents either a female or male from each litter. (A) Glutathione peroxidase (GPx) activity level by oxidation of NADPH per minute per milligram of protein in Se sufficient liver, heart, kidney, and lungs. (B) Cardiac glutathione peroxide activity level by oxidation of NADPH per minute per milligram of protein. (C) Renal glutathione peroxide activity level by oxidation of NADPH per minute per milligram of protein. (D) Pulmonary glutathione peroxide activity level by oxidation of NADPH per minute per milligram of protein N = 4 for all groups. Data and presented as mean (±SEM), * p < 0.05 vs. SeS control, by multiple comparison after one-way ANOVA, ∨ p < 0.05 vs. SeD <10 weeks by multiple comparisons after one-way ANOVA.