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Proportion of immature granulopoietic cells (“shift to the left”) as observed in the differential white cell count in different diseases. Compared to the reactive shift to the left in bacterial infectious diseases, CML is characterized by the presence of more immature granulopoietic cells in addition including myeloblasts. In AML “hiatus leucemicus” (Latin, meaning “leukemic gap”) usually is observed exhibiting myeloblasts and mature granulocytes only.
