Table 3.
Additional interventions for adults
| First author, year | Intervention | Mean costs (95% CI)/[SD] | Mean outcomes (95% CI)/[SD] | Incremental cost (95% CI)/[SD] | Incremental effect (95% CI)/[SD] | Incremental cost-effectiveness of intervention vs. TAU or BUC | CEAC | CEP |
|---|---|---|---|---|---|---|---|---|
| Meng, 2017 [22] | FSM (n = 89) | − $864a | NR | − $64 (− $206 to $77)a | 0.014 QALYs (− 0.008 to 0.036)a | FSM dominant | Y | Y |
| TAU (n = 48) | − $569a | NR | NA | NA | NA | |||
| Richardson, 2013 [24] | PR (n = 85) | NR | NR | £218 (− £474 to £911) | − 0.012 QALYs (− 0.088 to 0.065) | TAU dominates PR | Y | N |
| SL (n = 97) | NR | NR | £460 (− £250 to £1169) | − 0.042 QALYs (− 0.122 to 0.038) | TAU dominates SL | |||
| TAU (n = 92) | NR | NR | NA | NA | NA | |||
| Sabes-Figuera 2012, [25] | GET (n = 51) | £474b | 10.06 CFSa | £261 (£141 to £382) | 1.1 CFS (− 2.3 to 4.4)a | £987 per clinically significant improvement in CFS | Y | N |
| COUN (n = 58) | £651b | 8.62 CFSa | £423 (£288 to £559) | − 0.1 CFS (− 3.1 to 2.9)a | BUC dominates COU | |||
| BUC (n = 54) | £213b | 8.56 CFSa | NA | NA | NA |
BUC usual care plus self-help booklet, COUN counselling, CFS chronic fatigue syndrome, CI confidence interval, FSM fatigue self-management, GET graded exercise therapy, N no, NA not applicable, NR not reported, PR pragmatic rehabilitation, QALYs quality-adjusted life-years, SD standard deviation, SL supportive listening, TAU treatment as usual, Y yes, CEAC cost-effectiveness acceptability curve, CEP cost-effectiveness plane
aChange in effect/costs from baseline to follow-up
bHealthcare perspective only