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. 2021 Feb 12;14(2):149. doi: 10.3390/ph14020149

Table 1.

The list of reported miR-7 regulators in cancer.

I. Transcriptional Level
Transcription Factors MIR7-1 MIR7-2 MIR7-3 References
c-Myc [46]
HOXD10 [47]
HNF4 α [48]
FOXP3 [49]
RELA [50,51,52]
Usp18 [53]
II. Post-Transcriptional Level
pri-miRNA
Factor pri-miR-7-1 pri-miR-7-2
HuR/MSI2 [54]
QKI-5 [55]
QKI-6 [55]
SF2/ASF [56]
Mature miRNA Level
ceRNA Regulation Confirmed in:
circRNA
ciRS-7 brain, non-small cell lung cancer, esophageal squamous cell carcinoma, papillary thyroid cancer, colorectal cancer [59,60,61,62,63]
circSNCA brain [64]
circ_0006528 breast cancer [65,66]
circ-U2AF1 glioma [67]
circ_0000735 prostate cancer [68]
circ-ITCH osteosarcoma [69]
circ-TFCP2L1 breast cancer [70]
circ_0015756 hepatocellular carcinoma [71]
lncRNA
CASC21 colorectal cancer [73]
RHPN1-AS1 colorectal cancer,
hepatocellular carcinoma
[74,77]
RP4 colorectal cancer [75]
TINCR colorectal cancer [76]
KCNQ1OT1 hepatocellular carcinoma [78]
LINC00115 triple-negative breast cancer, lung adenocarcinoma [79,80]
MEG3 renal cell carcinoma [81]
HOTAIR breast cancer [82]
FOXD2-AS1 thyroid cancer [83]
SOX21 - AS1 cervical cancer [84]
UCA1 gastric cancer [85]
ANRIL acute lymphoblastic leukemia [86]
Cyrano brain [87]

↑, upregulation; ↓, downregulation.