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Change of treatment strategies for pediatric glioma. In treatment for pediatric glioma, because of advances of NGS, precision medicine is expected instead of evidence-based medicine. NCI-MATCH trial and Todai OncoPanel are representative precision medicine for pediatric glioma, and liquid biopsy is also expected in the future. RCT, randomized controlled trial; NGS, next-generation sequencing; CSF, cerebrospinal fluid.
