Figure 8.

SNHG7 silencing blocks xenograft tumor growth in vivo. Mice were injected with SW1990 cells transfected with sh-SNHG7 or sh-control. (A) Representative images of PC xenograft tissues are presented. (B) Tumor volume in treated mice. (C) Xenograft tumor weight in treated mice. mRNA expression levels of (D) SNHG7, (E) miR-146b-5p and (F) Robo1 in xenograft tumor were detected via reverse transcription-quantitative PCR. (G) Protein expression of Robo1 in xenograft tumor was measured by western blotting. ^*P<0.05 vs. the respective normal groups. miR, microRNA; Robo1, roundabout homolog 1; SNHG7, small nucleolar RNA host gene 7; sh, short hairpin RNA.